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Azithromycin is an antibiotic. It's widely used to treat chest infections such as pneumonia, infections of the nose and throat such as sinus infection (sinusitis), skin infections, Lyme disease, and some sexually transmitted infections.AzithAzithromycin alone and in combination with other medications is currently being studied for the treatment of coronavirus disease 2019 (COVID-19). Currently, azithromycin has been used with hydroxychloroquine to treat certain patients with COVID-19. However, there are mixed reports of effectiveness when azithromycin was used along with other medications to treat other viral respiratory infections. Azithromycin also has been used to treat bacterial infections in hospitalized patients with COVID-19. More information is needed before any conclusions can be made regarding the possible benefits and risks of using azithromycin either alone or in combination with hydroxychloroquine in patients with COVID-19.